Skip to Main content Skip to Navigation
Journal articles

Comparative expression of the four enamel matrix protein genes, amelogenin, ameloblastin, enamelin and amelotin during amelogenesis in the lizard Anolis carolinensis

Barbara Gasse 1, * Jean-Yves Sire 1 
* Corresponding author
Abstract : Background : In a recent study, we have demonstrated that amelotin (AMTN) gene structure and its expression during amelogenesis have changed during tetrapod evolution. Indeed, this gene is expressed throughout enamel matrix deposition and maturation in non-mammalian tetrapods, while in mammals its expression is restricted to the transition and maturation stages of amelogenesis. Previous studies of amelogenin (AMEL) gene expression in a lizard and a salamander have shown similar expression pattern to that in mammals, but to our knowledge there are no data regarding ameloblastin (AMBN) and enamelin (ENAM) expression in non-mammalian tetrapods. The present study aims to look at, and compare, the structure and expression of four enamel matrix protein genes, AMEL, AMBN, ENAM and AMTN during amelogenesis in the lizard Anolis carolinensis. Results : We provide the full-length cDNA sequence of A. carolinensis AMEL and AMBN, and show for the first time the expression of ENAM and AMBN in a non-mammalian species. During amelogenesis in A. carolinensis, AMEL, AMBN and ENAM expression in ameloblasts is similar to that described in mammals. It is noteworthy that AMEL and AMBN expression is also found in odontoblasts. Conclusions : Our findings indicate that AMTN is the only enamel matrix protein gene that is differentially expressed in ameloblasts between mammals and sauropsids. Changes in AMTN structure and expression could be the key to explain the structural differences between mammalian and reptilian enamel, i.e. prismatic versus non-prismatic.
Document type :
Journal articles
Complete list of metadata

Cited literature [59 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-01206550
Contributor : Gestionnaire HAL-UPMC Connect in order to contact the contributor
Submitted on : Tuesday, September 29, 2015 - 11:41:51 AM
Last modification on : Thursday, August 4, 2022 - 4:58:42 PM
Long-term archiving on: : Wednesday, December 30, 2015 - 10:35:31 AM

File

Gasse_2015_Comparative.pdf
Publication funded by an institution

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Citation

Barbara Gasse, Jean-Yves Sire. Comparative expression of the four enamel matrix protein genes, amelogenin, ameloblastin, enamelin and amelotin during amelogenesis in the lizard Anolis carolinensis. EvoDevo, BioMed Central, 2015, 6 (1), pp.29. ⟨10.1186/s13227-015-0024-4⟩. ⟨hal-01206550⟩

Share

Metrics

Record views

123

Files downloads

136