Skip to Main content Skip to Navigation
Journal articles

Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications

Abstract : The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament, its mechanical behavior is very dependent on the type of loading (compressive vs. tensile loading; static vs. cyclic loading; uniaxial vs. multiaxial) and the location around the root (cervical, middle, or apical). These different aspects of the periodontal ligament make it difficult to develop a functional biomaterial to treat periodontal attachment due to periodontal diseases. This review aims to describe the structural and biomechanical properties of the periodontal ligament. Particular importance is placed in the close interrelationship that exists between structure and biomechanics: the periodontal ligament structural organization is specific to its biomechanical environment, and its biomechanical properties are specific to its structural arrangement. This balance between structure and biomechanics can be explained by a mechanosensitive periodontal cellular activity. These specifications have to be considered in the further tissue engineering strategies for the development of an efficient biomaterial for periodontal tissues regeneration.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-03083933
Contributor : Ana-Maria Trunfio <>
Submitted on : Wednesday, December 23, 2020 - 2:19:19 PM
Last modification on : Friday, February 5, 2021 - 3:31:46 AM

File

Tissue engineering for periodo...
Files produced by the author(s)

Identifiers

Citation

Rémy Gauthier, Christophe Jeannin, N. Attik, Ana-Maria Trunfio-Sfarghiu, Kerstin Gritsch, et al.. Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications. Journal of Biomechanical Engineering, American Society of Mechanical Engineers, 2021, 143 (3), ⟨10.1115/1.4048810⟩. ⟨hal-03083933⟩

Share

Metrics

Record views

68

Files downloads

30