XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

Laia Richart; Mary-Loup Picod-Chedotel; Michel Wassef; Manon Macario; Setareh Aflaki; Marion Salvador; Tiphaine Héry; Aurélien Dauphin; Julien Wicinski; Véronique Chevrier; Sonia Pastor; Geoffrey Guittard; Samuel Le Cam; Hanya Kamhawi; Rémy Castellano; Géraldine Guasch; Emmanuelle Charafe-Jauffret; Edith Heard; Raphaël Margueron; Christophe Ginestier

doi:10.1016/j.cell.2022.04.034

Journal Articles Cell Year : 2022

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

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2
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Laia Richart

Function : Author

Mary-Loup Picod-Chedotel

Function : Author

Michel Wassef

Function : Author

Manon Macario

Function : Author

Setareh Aflaki

Function : Author

Marion Salvador

Function : Author

Tiphaine Héry

Function : Author

Aurélien Dauphin

Function : Author
PersonId : 757984
ORCID : 0000-0001-9744-8458
IdRef : 084653388

Julien Wicinski

Function : Author

Véronique Chevrier

Function : Author

Sonia Pastor

Function : Author

Geoffrey Guittard

Function : Author

Samuel Le Cam

Function : Author
PersonId : 1218503
ORCID : 0000-0002-7172-6226

Hanya Kamhawi

Function : Author
PersonId : 1218504
ORCID : 0000-0003-4252-9204

Rémy Castellano

Function : Author

Géraldine Guasch

Function : Author
PersonId : 801224
ORCID : 0000-0001-7362-9318

Emmanuelle Charafe-Jauffret

Function : Author
PersonId : 757496
ORCID : 0000-0002-0286-1299
IdRef : 188353305

Edith Heard

Function : Author

Raphaël Margueron

Function : Author

Centre de recherche de l'Institut Curie [Paris]

Génétique et Biologie du Développement

Christophe Ginestier

Function : Author
PersonId : 753078
IdHAL : christophe-ginestier
ORCID : 0000-0002-7477-3837
IdRef : 092140866

Centre de Recherche en Cancérologie de Marseille

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Life Sciences [q-bio]

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Last modification on : Monday, July 22, 2024-12:23:10 PM

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hal-03951681 , version 1 (22-07-2024)

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Attribution - NonCommercial

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HAL Id : hal-03951681 , version 1
DOI : 10.1016/j.cell.2022.04.034
PII : S0092-8674(22)00532-3

Cite

Laia Richart, Mary-Loup Picod-Chedotel, Michel Wassef, Manon Macario, Setareh Aflaki, et al.. XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation. Cell, 2022, 185 (12), pp.2164-2183.e25. ⟨10.1016/j.cell.2022.04.034⟩. ⟨hal-03951681⟩

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XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

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